Special due to Goldman Philanthropic Partnerships for funding this sequence.
00:00 – Introduction to Cutaneous T-cell Lymphoma
01:21 – The Challenge of Diagnosis
02:53 – Diagnosis, Staging Process, and Lesion Descriptions
06:42 – Topical Treatments
08:18 – Phototherapy and Radiation
10:06 – Summary and Conclusion
10:32 – Acknowledgments
Descriptions:
00:00 – Introduction to Cutaneous T-cell Lymphoma
Introduction to Dr. Nneka Comfere as a dermatologist and dermatopathologist. Her specialty is cutaneous T-cell lymphoma (CTCL), with a deal with its commonest subtype, mycosis fungoides.
01:21 – The Challenge of Diagnosis
Why diagnosing CTCL will be so tough, significantly in its early phases. The situation can mimic widespread, benign pores and skin rashes each clinically and beneath a microscope. This problem typically results in a delayed prognosis, with a median delay of three years. This delay can result in sufferers receiving inappropriate therapies earlier than getting the proper prognosis and therapy plan.
02:53 – Diagnosis, Staging Process, and Lesion Descriptions
Comprehensive course of for diagnosing and staging CTCL. The course of begins with a full-body pores and skin examination by a dermatologist to establish and describe any lesions. This is adopted by a number of pores and skin biopsies to extend the probabilities of an accurate prognosis. Additionally, blood exams and imaging scans like a CT or PET-CT scan are used to get a transparent view of inside organs and lymph nodes, which is essential for precisely staging the illness. Detailed description of the several types of lesions related to CTCL.
06:42 – Topical Treatments
First-line therapy choices for early-stage CTCL, that are primarily topical therapies. Use of corticosteroid lotions, topical nitrogen mustard (a topical chemotherapy agent), and topical retinoids, like bexarotene.
08:18 – Phototherapy and Radiation
Phototherapy, particularly narrow-band ultraviolet B (UVB) mild, is a handy and efficient possibility that may be performed in a clinic or at dwelling. Total pores and skin electron beam radiation remedy, a superficial type of radiation that’s extremely efficient for widespread illness that isn’t restricted to a single space.
10:06 – Summary and Conclusion
Key factors of the video, reinforcing the challenges of diagnosing early-stage CTCL, the strategies used to make an correct prognosis, and the widespread therapies obtainable.
10:32 – Acknowledgments
The video concludes with a thanks to the sufferers, the Mayo Clinic Lymphoma Disease-Oriented Group, and the Goldman Philanthropic Partnerships for his or her beneficiant reward that funded the video sequence.
Visit Mayo Clinic: https://mayocl.in/2COVmlm
Like Mayo Clinic on Facebook: https://www.facebook.com/mayoclinic/
Follow Mayo Clinic on Instagram: https://www.instagram.com/mayoclinic/
Follow Mayo Clinic on X, previously Twitter: https://x.com/MayoClinic
Follow Mayo Clinic on Threads: https://www.threads.net/@mayoclinic
