Provider Connections: Dr. Thomas Witzig on Relapsed Refractory Follicular Lymphoma

Special because of Goldman Philanthropic Partnerships for funding this collection.

00:00 – Introduction to Follicular Lymphoma
00:40 – Key Questions for Relapsed Lymphoma
02:08 – Treatment Options
02:43 – CAR-T Cell Therapy
03:20 – Bispecific Antibodies
04:00 – Zanabrutinib and Other Options
04:57 – A Personalized Treatment Plan
05:44 – Conclusion and Acknowledgments

Descriptions:
00:00 – Introduction to Follicular Lymphoma
Introduction of Dr. Thomas Witzig from the Mayo Clinic and the subject of debate: relapsed follicular lymphoma. Brief overview of what follicular lymphoma is and the way it usually presents.
00:40 – Key Questions for Diagnosis and Treatment
Outlines the essential questions a physician will ask a affected person with relapsed follicular lymphoma.
02:08 – Treatment Options for Relapsed Follicular Lymphoma
Various therapy approaches obtainable, Dr. Witzig explains that choices depend upon the affected person’s prior remedies.
02:43 – CAR-T Cell Therapy
CAR-T cell remedy, how a affected person’s T-cells are genetically modified to particularly goal and assault the lymphoma cells, leading to a excessive response fee.
03:20 – Bispecific Antibodies
Use of bispecific antibodies as one other therapy. These antibodies have two "heads", one which attaches to the tumor and one other that attaches to a affected person’s personal T-cells, bringing them collectively to battle the most cancers.
04:00 – Zanabrutinib and Other Options
The mixture of the capsule zanabrutinib with obinutuzumab. The R² routine (rituximab and lenalidomide), highlighting its effectiveness as a second-line therapy.
04:57 – A Personalized Approach to Treatment
Personalized therapy plan, medical doctors will take into account the affected person’s total well being and private emotions about their illness to create a plan that’s proper for them.
05:44 – Conclusion and Acknowledgments
The video concludes with a thanks to the sufferers, the Mayo Clinic group, and the Goldman Philanthropic Partnerships for his or her help in creating the video collection.