Probably essentially the most regarding facet of REM sleep habits dysfunction is that it’s typically a prodrome for Parkinson’s illness and different associated circumstances. In this podcast we discover present ideas of how dream enactment behaviors can progress to critical neurodegenerative issues.
00:39 How does a sleep problem evolve right into a broader neurodegenerative illness? (With visitor introduction: Dr. Bradley Boeve)
01:26 Understanding Synucleinopathies
03:22 The Braak Hypothesis
7:01 Explanation of protein misfolding
9:10 Emphasize that there is no such thing as a proof that Parkinson’s illness and associated circumstances are infectious
9:44 Challenges to the Hypothesis
13:18 – Conclusion and Sign-off
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