Updates from the 2024 ESC and AHA Scientific Statements on Cardiac Sarcoidosis

Guest: Leslie T. Cooper Jr., M.D.
Host: Kyle W. Klarich, M.D.

Cardiac sarcoidosis is a systemic, continual inflammatory dysfunction characterised by non-caseating, epithelioid cell granulomas which will contain many tissues and organs. The Heart Rhythm Society standards for analysis of cardiac sarcoidosis require a biopsy-proven analysis of extra-cardiac sarcoidosis. If extra-cardiac sarcoidosis is confirmed, CS is very possible when there’s proof of the next: (a) rhythm abnormalities in both ECG or Holter monitoring reminiscent of superior AVB (Mobitz sort II second-degree or third-degree AVB), sustained VT, and (b) LV dysfunction on echocardiography or CMR (LVEF lower than 40%) and/or appropriate sample on superior imaging modalities (cardiac PET, CMR). EMB, generally with electrogram steering to extend diagnostic yield, stays helpful in indeterminant circumstances, together with remoted cardiac involvement or suspected genetic etiology. Multidisciplinary groups consisting of respiratory physicians, rheumatologists, and cardiologists with experience in sarcoidosis in addition to different related subspecialties reminiscent of superior cardiac imaging specialists (CMR and nuclear drugs) and electrophysiologists are wanted to combine immunosuppression with arrhythmia and coronary heart failure administration.

Topics Discussed:
• What proportion of sufferers with cardiac sarcoidosis have lung or thoracic lymph node involvement?
• Which of the next are related to larger danger of coronary heart failure or ventricular arrhythmias in particular or possible cardiac sarcoidosis:
• Which of the next medicines could also be added to guideline directed therapies for the preliminary administration of acute and symptomatic cardiac sarcoidosis?

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